Info on (Anti-Estrogens) Clomid

Clomid Information:
Clomid is one of the most famous fertility medications. This is because it is most frequently used. Almost 25% of female infertility issues involve a problem with ovulation. This medicine, being as a fertility drug, is easy to take since it comes in the form of pills not injections. The side effects are also fewer. It is cost-effective compared to other fertility mediations. It proves to be effective in stimulating ovulation 80% of the time.

Clomid is the formal brand name for the fertility medication clomiphene citrate. It may also be sold under the brand name Serophene. Whether you take the brand name Clomid, Serophene, or a generic version of clomiphene citrate, these are all the same medicine.

Clomid is meant for making the recovery of natural testosterone production after steroid usage, and improving testosterone production of steroid users. It is also very effective in lessening risk of gynecomastia during a series using aromatizable steroids. Although it is claimed that this medicine stimulates the production of LH, and as a result testosterone, Clomid actually works not by stimulation of the hypothalamus and pituitary, but by jamming their reserve of estrogen.

This drug is a mixed estrogen activator/blocker. When it is bound to the estrogen receptor, it puts it in a somewhat unusual conformation, unlike estradiol. The estrogen receptor needs binding of estrogen or a drug at its binding spot, and also the binding of any of numerous cofactors at various sites. Without this, the estrogen receptor is not active. Various tissues use different cofactors, and some of these cofactors are able to connect to the estrogen receptor/Clomid complex, while others are blocked because of the change in shape. As a result, Clomid acts as an antagonist in some tissues. The cofactor used in that tissue is not able to connect, and so the receptor does not become active. In others, Clomid works as an activator as the cofactors used in that tissue can bind.

This medication is an effective antagonist in the hypothalamus and in breast tissue. It is an effective agonist in bone tissue, and for improving blood cholesterol levels. It can also reduce the undesirable outcome of muscle tissue pain during activity. This medicine seems to have some effect on mood, which can be helpful. It can improve relationships with women by improving understanding in males taking it. It can also help you with depression.

Follow the recommendation of your doctor when taking Clomid. The often-recommended dosage of Clomid is 50 mg, taken for five days, on days 3 through 7 of your steroid therapy, or days 5 through 9 of your therapy. Since ovulation and pregnancy rates have been shown to be similar, no matter if you started this medicine on day two, three, four, or five, you should not be worried if your doctor gives you a slightly different prescription.

Before usage:

Before you start to take Proviron, your doctor will conduct an examination of the prostate. Your doctor will also note your family medical history and perform other tests including a blood test.

Tell your doctor if you:

•have a heart condition
•have impaired kidney function
•suffer from high blood pressure
•suffer from migraines
•have epilepsy
•have diabetes
•have porphyria – a rare metabolising disorder
Tell your doctor if you are taking any other medicines, including those that you buy without a prescription from your pharmacy, supermarket or health food shop.

Some medicines may affect the way others work. Your doctor or pharmacist will be able to tell you what to do when taking Proviron with other medicines.

Some medicines may interfere with the absorption of Proviron. These medicines include: Phenobarbital, Phenytoin.

Proviron may interfere with the absorption of the following medicines: Cyclosporin, Antidiabetics, Thyroxine, Anticoagulants such as warfarin.

Do not take Proviron if you:

•have an allergy to mesterolone or any of the ingredients in Proviron
•have cancer of the prostate
•have previous or existing liver tumours
•have high blood calcium levels
Do not take Proviron after the expiry date printed on the pack.

How to take Proviron

How much to take
Your doctor or pharmacist will tell you how much and how often you should take Proviron. For Proviron to work best it is very important to take Proviron exactly as your doctor tells you. You should not exceed the recommended dose your doctor has prescribed for you.

How to take it
Swallow the tablet whole with a glass of water or other fluid. Do not chew the tablets.

When to take it
Generally initial treatment consists of 1-2 tablets three times per day which may be reduced after some months.

If you forget to take it
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking it as you would normally. Do not take a double dose to make up for the dose that you missed. If you are not sure what to do, ask your doctor or pharmacist. If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.

If you take too much (overdose)
Immediately telephone your doctor, or the Poisons Information Centre, or go to the accident and emergency department at your nearest hospital, if you think you or anyone else may have taken too much Proviron. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

While using Proviron:

Your doctor will conduct regular examinations of the prostate. In rare cases non-cancerous and in even rarer cases cancerous liver tumours leading in isolated cases to life-threatening bleeding within the stomach have been observed after the use of hormonal substances such as the one contained in Proviron. Tell your doctor if you have any unusual abdominal complaints which do not disappear within a short time.

Do not give your Proviron tablets to anyone else, even if they have the same condition as you.

Proviron possible side effects:

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Proviron.

Tell your doctor if you notice any of the following:

•headache
•pain in liver area
•symptoms of an enlarged prostate such as changes in urination, or blood in the urine or ejaculate
•pain in lower back or abdomen
•pain in pelvic area
•loss of appetite
•unexplained weight loss
•depression
•aggression
•acne
•hirsutism
If frequent or persistent erections occur, the doctor may reduce the dose or discontinue treatment in order to avoid injury to the penis.

Other side effects not listed above may also occur in some patients. Tell your doctor if you notice anything else that is making you feel unwell.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

How to store Proviron:

Keep your tablets in the original packaging until it is time to take them. If you take the tablets out of the bottle or the blister pack they may not keep well.

Keep your tablets in a cool dry place where the temperature stays below 30oC. Do not leave the tablets in the car on hot days.

Keep your tablets where children cannot reach them.

Note:

This leaflet answers some common questions about Proviron. It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking Proviron against the benefits they expect it will have for you. If you have any concerns about taking this medicine, ask your doctor or pharmacist.